Light’s Impact on Calcium Signaling & DNA Regulation (collection)
A light-induced small G-protein gem limits the circadian clock phase-shift magnitude by inhibiting voltage-dependent calcium channels Author links open overlay panelMasahiro Matsuo 12, Kazuyuki Seo 1, Akiyuki Taruno 34, Yasutaka Mizoro 1, Yoshiaki Yamaguchi 1, Masao Doi 1, Rhyuta Nakao 5, Hiroshi Kori 6, Takaya Abe 4 7, Harunori Ohmori 4, Keiko Tominaga 89, Hitoshi Okamura 1101 Calcium signaling is pivotal to the circadian clockwork in the suprachiasmatic nucleus(SCN), particularly in rhythm entrainment to environmental light-dark cycles. Here, we show that a small G-protein Gem, an endogenous inhibitor of high-voltage-activated voltage-dependent calcium channels … Read more